In the context of the regional protected area system, Monte Genzana Alto Gizio Nature Reserve plays a very important role, since it represents an ecological corridor between Abruzzo National Park and Maiella National Park. Its territory, developing between the 530m asl of the river Gizio and the 2,170m asl of Mt. Genzana, consists of very different natural environments preserving a considerable heritage of flora and fauna. The presence of Pettorano sul Gizio historical town center in the protected area is a unique feature characterizing the Nature Reserve.